Recently we have upgraded the VCSA after that noticed some performance issue while loading vcenter inventory.
Check the disk space "df -h" via SSH into the vCenter server appliance.

(/dev/mapper/core_vg-core 25G 25G 0M 100% /storage/core)
It looks storage/core is near to full.
/storage/core # ls -l (remove earlier month of core.vpxd-worker.45xxxxx).
root@/storage/core]# rm -f core.vpxd-worker.45xxxx

Chech VC services status.

If you want to extend disk ? resize VMDK then run this command.

/usr/lib/applmgmt/support/scripts/autogrow.sh

# service vmware-vpxd status.

Hope this will be informative for you, Thank you for Reading !